787595-36-2Relevant academic research and scientific papers
Catalytic enantioselective cascade Michael/cyclization reaction of 3-isothiocyanato oxindoles with exocyclic α,β-unsaturated ketones: En route to 3,2′-pyrrolidinyl bispirooxindoles
Kayal, Satavisha,Mukherjee, Santanu
, p. 10175 - 10179 (2016)
Cascade Michael/cyclization reactions between 3-isothiocyanato oxindoles and exocyclic α,β-unsaturated ketones are shown to proceed efficiently in the presence of a quinine-derived tertiary amino-squaramide catalyst and furnish 3,2′-pyrrolidinyl bispirooxindoles containing two spiro-quaternary and three contiguous stereocenters as a single diastereomer with excellent enantioselectivities (up to 99:1 er).
Dimethyldioxirane oxidation of exocyclic (E,E)-cinnamylideneketones
Lvai, Albert,Silva, Artur M. S.,Santos, Clementina M. M.,Cavaleiro, Jos A. S.,Jek, Jzsef
experimental part, p. 82 - 89 (2009/07/25)
Exocyclic (E,E)-cinnamylideneketones were oxidized by an excess of isolated dimethyldioxirane (DMDO, in acetone solution) at room temperature, providing diastereomeric mixtures of the ,:,-diepoxides. In the case of derivatives bearing an ortho-nitrocinnam
