78761-39-4Relevant academic research and scientific papers
N, O-ligand accelerated zinc-catalyzed transesterification of alcohols with vinyl esters
Mino, Takashi,Hasegawa, Tae,Shirae, Yoshiaki,Sakamoto, Masami,Fujita, Tsutomu
, p. 4389 - 4396 (2008/02/13)
N-Phenyldiethanolamine (1f) is an efficient ligand for zinc-catalyzed transesterification of alcohols with vinyl acetate (R3 = Me) at room temperature. In the case of using other vinyl esters (R3 = Et, n-Pr, Ph), the corresponding products were easily obtained in the presence of pyridine-type ligand 2 instead of aminoalcohol 1f.
Iron perchlorate on silica gel as multi-purpose reagent for catalysis of closure and rupture of carbon-oxygen bond in epoxides, alcohols, and esters
Salechi,Khodaei,Ghareghani,Motlagh
, p. 794 - 796 (2007/10/03)
Aliphatic alcohols and water in the presence of catalytic amounts of Fe3+ ion introduced as iron(III) perchlorate on silica gel carrier perform efficient regiospecific opening of an epoxy ring. Carbon acids esterification with various type alcohols was carried out using the system Fe(ClO4)3-silica gel in dichloromethane under conditions excluding solvolysis. Acetylation and formylation of alcohols was performed by efficient transesterification with ethyl acetate and ethyl formate.
Addition of organocopper reagents to allylic acrylates - The preparation of γ, δ-unsaturated acids and subsequent functionalization to γ-lactones
Eriksson, Magnus,Hjelmencrantz, Anders,Nilsson, Martin,Olsson, Thomas
, p. 12631 - 12644 (2007/10/02)
Conjugate addition of monoorganocopper compounds with iodotrimethylsilane (TMSI) or lithium diorganocuprates, with or without halosilanes, to allylic acrylates give allylic silyl ketene acetals/ester enolates. These can undergo Claisen rearrangement to give diastereomeric mixtures of γ, δ-unsaturated acids after aqueous work-up. For organocuprates, the diastereomeric ratio is strongly affected by the halosilane. Either diastereomer can be obtained as major product by proper choice of copper reagent. Cyclization of the acids followed by reduction gives γ-lactones in good yields. A copper iodide/dimethyl sulfide complex is introduced as an excellent precursor to organocopper reagents.
DIRECT BUTYROLACTONE PRODUCTION USING TIN HYDRIDE
Belletire, J. L.,Mahmoodi, N. O.
, p. 4363 - 4366 (2007/10/02)
Use of HSnBu3 for the reductive cyclization of suitable alpha-bromo allylic esters affords 2,3-disubstituted butyrolactones.
