78771-13-8

Basic information

• Product Name: Sarmazenil
• Synonyms: Sarmazenil;7-Chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester;ethyl 7-chloro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate(WXG00129)
• CAS NO: 78771-13-8
• Molecular Formula: C₁₅H₁₄ClN₃O₃
• Molecular Weight: 319.743
• Mol File: 78771-13-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 224 °C
• Boiling Point: 554°Cat760mmHg
• Flash Point: 288.9°C
• Appearance: /
• Density: 1.43g/cm³
• Vapor Pressure: 2.57E-12mmHg at 25°C
• Refractive Index: 1.658
• PKA: 0.70±0.20(Predicted)
• CAS DataBase Reference: Sarmazenil(CAS DataBase Reference)
• NIST Chemistry Reference: Sarmazenil(78771-13-8)
• EPA Substance Registry System: Sarmazenil(78771-13-8)

Safety Data

• Hazardous Substances Data: 78771-13-8(Hazardous Substances Data)

Usage

Uses

Sarmazenil is a benzodiazepine receptor antagonist.

InChI:InChI=1/C15H14ClN3O3/c1-3-22-15(21)13-11-7-18(2)14(20)12-9(16)5-4-6-10(12)19(11)8-17-13/h4-6,8H,3,7H2,1-2H3

Upstream product

• 3400-09-7 dichloroamine 
• 78755-99-4 3,4-dihydro-4-methyl-6-chloro-2H-1,4-benzodiazepine-2,5(1H)-dione 
• 99-97-8 Dimethyl-p-toluidine 

Downstream Products

• 172407-34-0 7-chloro-3-(5-dibutylaminomethyl-1,3,4-oxadiazol-2-yl)-5-methyl-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one 
• 122384-14-9 L-663581 

Relevant articles and documents

Imidazodiazepine derivative

The present invention relates to compound 7-Chloro-3-(5-dimethylaminomethyl-[1,2,4]oxadiazol-3-yl)-5-methyl-4,5-dihydro-imidazo[1,5-a][1,4]benzodiazepin-6-one (I) and to the use of the compound of formula I for the manufacture of medicaments to be used as anxiolytic and/or anticonvulsant and/or non-sedative sleep-inducing medicaments.