78790-83-7

Usage

Uses

Used in Medicinal Chemistry:
Ethyl 3-aminothieno[2,3-c]pyridine-2-carboxylate is used as a building block for the synthesis of potential drug candidates due to its unique molecular structure and pharmacological properties. Its presence in the synthesis process can contribute to the development of new therapeutic agents with novel mechanisms of action.
Used in Drug Discovery:
In the field of drug discovery, Ethyl 3-aminothieno[2,3-c]pyridine-2-carboxylate is utilized as a starting point for the design and development of new pharmaceuticals. Its potential biological activities, such as enzyme inhibition or receptor binding, make it a valuable component in the creation of innovative treatments for various diseases and conditions.
Used in Enzyme Inhibition:
Ethyl 3-aminothieno[2,3-c]pyridine-2-carboxylate is used as an enzyme inhibitor, targeting specific enzymes that play a role in disease progression. By inhibiting these enzymes, the compound can potentially modulate biological pathways and contribute to therapeutic effects.
Used in Biological Receptor Binding:
Ethyl 3-aminothieno[2,3-c]pyridine-2-carboxylate is also used as a ligand for biological receptors, interacting with specific receptors to elicit a desired biological response. This interaction can be harnessed to develop drugs that target receptor-mediated pathways, offering new avenues for treatment of various disorders.
Used in Pharmaceutical Industry:
Ethyl 3-aminothieno[2,3-c]pyridine-2-carboxylate is used in the pharmaceutical industry as a key component in the development of new drugs. Its unique structure and potential applications in medicinal chemistry make it a valuable asset in the pursuit of novel therapeutic agents.

Upstream product

• 13958-98-0 3-bromo-4-cyanopyridine 
• 623-51-8 ethyl 2-sulfanylacetate 
• 68325-15-5 3-chloro-isonicotinonitrile 
• 20577-26-8 2-bromonicotinonitrile 

Downstream Products

• 63326-75-0 thieno[2,3-c]pyridin-3-amine 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6

The present disclosure relates to compounds capable of modulating the activity of NR2F6. The compounds of the disclosure may be used in methods for the prevention and/or the treatment of diseases and disorders associated with modulating NR2F6 activity.

TRICYCLIC SUBSTITUTED THIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE

In its many embodiments, the present invention provides provides certain iminothiazine dioxide compounds, including compounds Formula (I): (I) and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomero

Raf inhibitor compounds and methods of use thereof

Compounds of Formula I are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

ETUDE DES REACTIONS DE SRN1-PARTIE 10 ACTION DE SULFANIONS SUR LES HALOGENURES D'ARYLE FONCTIONNALISES. SYNTHESE DIRECTE DE BENZOTHIOPHENES ET THIENOPYRIDINES

Functionalized aromatic halides Ar1XY (Ar1=C6H4, Y=OCH3,CONH2,CN,COCH3,CHO,COC6H5) undergo SRN1 reactions with sulphur anions -SR, either simple (R=C2H5,CH2C6H5) or functionalized (R=(CH2)2OH,(CH2)2CO2Et,CH2CO2Et).Products Ar1YS- formed from the fragmentation of the radical anion Ar1YSR- are related to the redox potential of the aryl moiety Ar1Y and with the energy of the bond S-R.In the heterocyclic series (Ar2=pyridine, Ar3=quinoline) a similar relationship appears but a competitive SN(AR) reaction occurs for pyridine substrates bearing an electron withdrawing group.A direct synthesis of benzothiophen via SRN1 reaction and an improved synthesis of thienopyridines based on the SN(Ar) reaction are reported.

Chemoselective Reactions of 3-Chloroisonicotinonitrile

Chemoselective reactions of 3-chloroisonicotinonitrile (1) with nucleophiles are described.Treatment of 1 with sodium methoxide/methanol results in formation of the imino ether, which can be further elaborated into a triazole ring.However, when 1 is react