78808-22-7Relevant academic research and scientific papers
An X-ray crystallographic and NMR study of the regioselective partial hydrolysis of N-benzylcamphorimide
English, Robin B.,Kaye, Perry T.,Learmonth, Robin A.,Molema, Warner
, p. 22 - 27 (2007/10/03)
Single-crystal X-ray analyis and one-and two-dimensional NMR spectroscopy has been used to establish the structure of the major regioisomeric product from partial hydrolysis of N-benzylcamphorimide, and to elucidate an unexpected intramolecular rearrangement.
Regioselectivity and Stereoselectivity in the Reaction of cis-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic Anhydride (cis-Camphoric Anhydride) with Chiral Primary Amines
Bell, Kevin H.
, p. 665 - 670 (2007/10/02)
The reaction between primary amines and cis-1,2,2-trimethylcyclopentane-1,3-dicarboxylic anhydride (3) has been shown to be regioselective for the less hindered carbonyl group.Kinetic resolution was observed when racemic primary amines and the (1R,3S) anhydride (3) were used.Similar stereoselectivity was found in the alternative reaction between racemic (3) and optically active primary amines.In both cases, the absolute configuration of the more reactive enantiomeric amine or anhydride could be correlated with a model (7).The use of (3) is recommended for the prediction of the absolute configurations of racemic and optically active primary amines.
