78831-23-9Relevant academic research and scientific papers
The Synthesis of Pyridine Derivatives from 3-Formylchromone
Hass, Georges,Stanton, James L.,Sprecher, Andreas von,Wenk, Paul
, p. 607 - 612 (2007/10/02)
3-Formylchromone (1) reacts with active methylene derivatives to yield condensation products 2a-d, 10, 11 and 12.Treatment of 2a-d with ammonia or methylamine gives pyridines 3-6.Alternatively, reaction of 1 with enamine derivatives yields pyrido compounds 15,17,19,21,23 and 28 in one step.Factors determining the formation and regiospecifity of the pyridine ring forming reactions are also discussed.
