78833-92-8

Basic information

• Product Name: methyl p-nitrobenzyl 2-(4-methylthio-2-oxoazetidin-1-yl)malonate
• CAS NO: 78833-92-8
• Molecular Weight: 368.367
• Mol File: 78833-92-8.mol

Chemical Properties

• CAS DataBase Reference: methyl p-nitrobenzyl 2-(4-methylthio-2-oxoazetidin-1-yl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl p-nitrobenzyl 2-(4-methylthio-2-oxoazetidin-1-yl)malonate(78833-92-8)
• EPA Substance Registry System: methyl p-nitrobenzyl 2-(4-methylthio-2-oxoazetidin-1-yl)malonate(78833-92-8)

Safety Data

• Hazardous Substances Data: 78833-92-8(Hazardous Substances Data)

Upstream product

• 68290-19-7 (2-methylsulfanyl-4-oxo-azetidin-1-yl)-acetic acid methyl ester 
• 4457-32-3 4-nitrobenzyl chloroformate 

Relevant articles and documents

A Carbon-Carbon Bond Formation Reaction at the C-4 Position of a β-Lactam

Upon treatment with various organolithiums, 4-acetoxyazetidin-2-one(10) afforded the corresponding carbon-displaced compounds (11),(12), and (13). 4-(3-diazo-3-ethoxycarbonyl-2-oxopropyl)azetidin-2-one (15) was also synthesised from (10) and ethyl α-diazoacetoacetate in the presence of lithium hexamethyldisilazide in one step.The diazo-compound (15) was thermally cyclised to the bicyclic keto-ester (17) in the presence of rhodium acetate.