78839-91-5

Upstream product

• 108-98-5 thiophenol 
• 638-29-9 n-valeryl chloride 
• 56379-68-1 S-phenyl thio-n-valerate 
• 2524-64-3 chlorophosphoric acid diphenyl ester 

Downstream Products

• 78839-93-7 (E)-1-butylidene-2-heptenyl phenyl sulfide 
• 20032-49-9 1-methyl-1-pentenyl phenyl sulfide 
• 591-78-6 n-hexan-2-one 
• 78839-95-9 1-(phenylethynyl)-1-pentenyl phenyl sulfide 
• 78839-96-0 (E/Z)-pent-1-enyl phenyl sulfide 
• 78839-94-8 1-ethyl-1-pentenyl phenyl sulfide 

Relevant academic research and scientific papers

CROSS-COUPLING REACTION BETWEEN ENOL PHOSPHATES AND ORGANOALUMINIUM COMPOUNDS IN THE PRESENCE OF PALLADIUM(0) CATALYST.

The title reaction in the presence of a catalytic amount of tetrakis(triphenylphosphine)palladium(0) affords alkylative coupling products in good to excellent yields in 1,2-dichloroethane at room temperature. This coupling reaction under C(sp**2)-O cleavage proceeds stereospecifically. The reaction does not affect a coexisting vinyl sulfide group. This feature enables 1,2- and 1,3-carbonyl transposition with or without alkylation via phenylthio-substituted enol phosphates.

Pd(O) PROMOTED ALKYLATION OF ENOL PHOSPHATES WITH ORGANOALUMINIUM COMPOUNDS AND ITS SYNTHETIC APPLICATIONS

Keto carbonyl 1,2- and 1,3-transpositions with and without alkylation of the substrate are described together with ketone synthesis from thiocarboxylic S-ester.