78867-90-0Relevant academic research and scientific papers
Dynamic kinetic resolution of N-benzoyl-DL-amino acids via peptide bond forming reactions
Miyazawa, Toshifumi,Hamada, Takashi
, p. 419 - 422 (2011/12/04)
Dynamic kinetic resolution (DKR) was demonstrated in the carbodiimide-mediated couplings of N-benzoyl-DL-amino acids with L-amino acid esters: the yields of the D-L-peptides significantly exceeded 50% in some cases. N-benzoyl-DL-t-leucine afforded the D-L-peptide almost exclusively (up to 96% yield) in the reaction with methyl L-prolinate, which is the most efficient DKR obtained in the field of amino acids and derivatives.
Studies on the Diastereoisomeric and Conformational Aspects of Benzoyl Dipeptide Esters, as a Means of assessing Racemisation using Nuclear Magnetic Resonance Spectroscopy
Davies, John S.,Thomas, R. John
, p. 1639 - 1646 (2007/10/02)
Distinct methyl ester signals in the 1H n.m.r. spectra of diastereoisomeric forms of benzoyl dipeptide methyl esters provide a means of estimating the isomer composition of diastereoisomeric mixtures.Analysis of the mixture derived from peptide-coupling r
