78867-95-5Relevant academic research and scientific papers
Assessment of Racemisation in N-Alkylated Amino-acid Derivatives during Peptide Coupling in a Model Dipeptide System
Davies, John S.,Mohammed, A. Karim
, p. 2982 - 2990 (2007/10/02)
N.m.r. analysis of diastereoisomeric benzoyl dipeptide esters has been used to monitor racemisation during the coupling of benzoyl-N-alkylated amino-acids to alanine and valine methyl esters.Results confirm the greater susceptibility of these amino-acids
Studies on the Diastereoisomeric and Conformational Aspects of Benzoyl Dipeptide Esters, as a Means of assessing Racemisation using Nuclear Magnetic Resonance Spectroscopy
Davies, John S.,Thomas, R. John
, p. 1639 - 1646 (2007/10/02)
Distinct methyl ester signals in the 1H n.m.r. spectra of diastereoisomeric forms of benzoyl dipeptide methyl esters provide a means of estimating the isomer composition of diastereoisomeric mixtures.Analysis of the mixture derived from peptide-coupling r
