78874-27-8 Usage
Uses
Used in Pharmaceutical Industry:
5-(2,4-DICHLORO-PHENYL)-4H-PYRAZOLE-3-CARBOXYLIC ACID is used as a key intermediate in the synthesis of various pharmaceuticals for its potent inhibitory effects on COX-2, which contribute to its anti-inflammatory and analgesic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 5-(2,4-DICHLORO-PHENYL)-4H-PYRAZOLE-3-CARBOXYLIC ACID is utilized as a component in the development of agrochemicals, leveraging its versatile chemical properties to enhance crop protection and yield.
Used in Organic Synthesis:
5-(2,4-DICHLORO-PHENYL)-4H-PYRAZOLE-3-CARBOXYLIC ACID serves as an essential organic intermediate in the synthesis of a range of organic compounds, facilitating the creation of new molecules with potential applications in various industries.
Used in Cancer Research:
5-(2,4-DICHLORO-PHENYL)-4H-PYRAZOLE-3-CARBOXYLIC ACID is employed as a research compound in cancer studies, exploring its potential to contribute to the development of novel therapeutic agents for the treatment of various types of cancer.
Used in Neurodegenerative Disorder Research:
5-(2,4-DICHLORO-PHENYL)-4H-PYRAZOLE-3-CARBOXYLIC ACID is also utilized in the investigation of treatments for neurodegenerative disorders, capitalizing on its diverse properties to potentially develop new therapeutic approaches for conditions such as Alzheimer's and Parkinson's diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 78874-27-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,8,7 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 78874-27:
(7*7)+(6*8)+(5*8)+(4*7)+(3*4)+(2*2)+(1*7)=188
188 % 10 = 8
So 78874-27-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H6Cl2N2O2/c11-5-1-2-6(7(12)3-5)8-4-9(10(15)16)14-13-8/h1-4H,(H,13,14)(H,15,16)/p-1
78874-27-8Relevant academic research and scientific papers
NOVEL NK-3 RECEPTOR SELECTIVE ANTAGONIST COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN NK-3 RECEPTORS MEDIATED DISORDERS
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Page/Page column 115, (2011/10/13)
The present invention is directed to novel compounds of formula I and their use as therapeutic compounds.
Design and synthesis of pyrazole derivatives as potent and selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP)
Sidique, Shyama,Ardecky, Robert,Su, Ying,Narisawa, Sonoko,Brown, Brock,Millan, Jose Luis,Sergienko, Eduard,Cosford, Nicholas D.P.
scheme or table, p. 222 - 225 (2009/05/07)
Tissue-nonspecific alkaline phosphatase (TNAP) plays a central role in regulating extracellular matrix calcification during bone formation and growth. High-throughput screening (HTS) for small molecule TNAP inhibitors led to the identification of hits in
Some Reactions of β-Aroylacrylic Acid Epoxides
Elkasaby, M. A.,Noureldin, N. A.
, p. 366 - 368 (2007/10/02)
β-Aroylacrylic acids (I) on reaction with hydrogen peroxide give α,β-epoxy-β-aroylacrylic acids (II) which on treatment with sodium hydroxide afford a mixture of arylmethyl 1,2-diketone (III) and arylmethyl glycollic acid (IV).The mixture is separated bei
