78877-58-4Relevant academic research and scientific papers
Synthesis of Optically Active α-Methylene β-Lactams through Lipase-Catalyzed Kinetic Resolution
Adam, Waldemar,Groer, Peter,Humpf, Hans-Ulrich,Saha-Moeller, Chantu R.
, p. 4919 - 4922 (2007/10/03)
A convenient method for the preparation of the hitherto unknown chiral α-methylene β-lactam derivatives 5a,b is reported. The optically active α-methylene β-lactams 5a-c, and their corresponding amino acids 6a-c have been readily made available through li
Synthesis of 3-Methyleneazetidin-2-one Derivatives from α-Keto-amides
Adlington, Robert M.,Barrett, Anthony G.M.,Quayle, Peter,Walker, Andrew,Betts, Michael J.
, p. 605 - 612 (2007/10/02)
Several α-methyleneazetidin-2-one derivatives (CH2=CCONR1CHR2, R1 = cyclohexyl, PhCH2; R2 = H, Me, Et, Prn, etc.) were prepared from the 2-(2,4,6-tri-isopropylbenzenesulphonylhydrazones) of primary α-
Novel Syntheses of 3-Methylene-azetidin-2-one Derivatives and Related Systems
Adlington, Robert M.,Barrett, Anthony G. M.,Quayle, Peter,Walker, Andrew,Betts, Michael J.
, p. 404 - 405 (2007/10/02)
Syntheses of the title compounds via 1-lithio-oxy-1-lithio-amino-allene derivatives or lithium phenylethynolate are described.
