78888-52-5 Usage
Uses
Used in Pharmaceutical Industry:
1-(3-methylphenyl)-2-(piperidin-1-ylmethyl)prop-2-en-1-one is used as an intermediate for the synthesis of various pharmaceuticals due to its complex structure and potential pharmacological properties. The presence of the piperidin-1-ylmethyl group suggests bioactivity in the central nervous system, while the propenone moiety indicates possible reactivity in chemical reactions, and the 3-methylphenyl group provides specific steric and electronic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(3-methylphenyl)-2-(piperidin-1-ylmethyl)prop-2-en-1-one is used as an intermediate for the development of agrochemicals, leveraging its structural complexity and potential reactivity to create new compounds with desired biological activities.
Used in Materials Science:
1-(3-methylphenyl)-2-(piperidin-1-ylmethyl)prop-2-en-1-one may also be utilized in materials science for the development of new materials, given its unique structural features and potential for various chemical reactions.
Used in Research Applications:
1-(3-methylphenyl)-2-(piperidin-1-ylmethyl)prop-2-en-1-one is used as a building block in research applications to develop new drugs and biologically active molecules, taking advantage of its complex structure and the potential pharmacological properties conferred by the piperidine ring and other functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 78888-52-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,8,8 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 78888-52:
(7*7)+(6*8)+(5*8)+(4*8)+(3*8)+(2*5)+(1*2)=205
205 % 10 = 5
So 78888-52-5 is a valid CAS Registry Number.
78888-52-5Relevant academic research and scientific papers
N-substituted alpha-aminoalkylacrylophenones and some related compounds: a new class of spermicidal agents.
Gupta,Nautiyal,Jhingran,Kamboj,Setty,Anand
, p. 303 - 307 (2007/10/02)
The results of a screening program to test the spermicidal effectiveness of several compounds is presented. The program was initiated after N-substituted 3-aminoacrylophenones were found to have unexpected spermicidal activity. The compounds had been synthesized as possible antiinflammatory agents. This result prompted the synthesis and screening of N-substituted alpha-aminomethylacrylophenones, alpha-(2-aminomethyl)acrylophenones and 3-N-substituted-2-methyleneindan-1-ones. The starting materials, substituted acetophenones, for the synthesis of N-substituted alpha-aminomethylacrylophenones were either commercial products or obtained by standard methods. N-substituted amino-butyrophenone was reacted with paraformaldehyde to yield the alpha-(2 aminoethyl)acrylophenones. A series of reactions was undertaken to synthesize 2-methyleneindan-1-ones. The preparation of each is detailed and molecular formulas are provided. Spermicidal activity was assessed by dissolving the compound in physiological saline at different concentrations. 2 drops of rat sperm suspension or human semen were placed on a slide, followed by 2 drops of a compound solution. Control slides of physiological saline were prepared. The contents were mixed for approximately 5 seconds and examined under a phase contrast microscope. The results were considered positive if 100% of the spermatozoa became immotile instantaneously. Several of the compounds showed marked spermicidal activity.
