78891-83-5Relevant academic research and scientific papers
Synthetic Routes to Benzanthracenes via Transient 1-Benzylisobenzofuran Derivatives
Smith, James G.,Welankiwar, Sudha S.,Chu, Noreen G.,Lai, Eric H.,Sondheimer, Susan J.
, p. 4658 - 4662 (2007/10/02)
A synthetic route to 7-acetoxybenzanthracenes is described based on the generation of 1-benzylisobenzofurans and their capture with methyl acrylate in a Diels-Alder reaction.The 1,4-epoxy-1,2,3,4-tetrahydronaphthalene derivatives so formed are aromatized to naphthoate esters under acidic conditions and hydrolyzed to the naphthoic acids, and these are cyclized to the 7-acetoxybenzanthracenes with zinc chloride in acetic anhydride.
