78903-83-0

Upstream product

• 82671-13-4 ethyl 7-(4-acetyl-1-piperazinyl)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate 
• 13889-98-0 N-acetylpiperidine 
• 84233-60-3 ethyl 7-(4-acetyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate 
• 56654-05-8 ethyl 7-chloro-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate 
• 54132-41-1 ethyl 7-(4-acetyl-1-piperazinyl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate 
• 87938-96-3 7-(4-Acetyl-piperazin-1-yl)-6-amino-1-ethyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 87939-04-6 7-(4-Acetyl-piperazin-1-yl)-1-ethyl-6-nitro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 87938-98-5 C₁₉H₂₃N₆O₄⁽¹⁺⁾*F₆P^(1-) 
• 16013-85-7 2,6-dicholoro-3-nitropyridine 
• 84233-59-0 2-(4-acetyl-1-piperazinyl)-6-amino-3-fluoropyridine 
• 84209-35-8 1-[4-(6-Chloro-3-nitro-pyridin-2-yl)-piperazin-1-yl]-ethanone 
• 84209-36-9 2-(4-acetyl-1-piperazinyl)-6-amino-3-nitropyridine 
• 84209-41-6 6-acetylamino-2-(4-acetyl-1-piperazinyl)-3-fluoropyridine 
• 84209-38-1 6-acetylamino-2-(4-acetyl-1-piperazinyl)-3-aminopyridine 

Relevant academic research and scientific papers

Pyridonecarboxylic acids as antibacterial agents. 2. Synthesis and structure-activity relationships of 1,6,7-trisubstituted 1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids, including enoxacin, a new antibacterial agent

The title compounds having nitro, amino, cyano, chloro, or fluoro as the C-6 substituent were prepared. Introduction of the chloro and cyano groups at C-6 was accomplished by the Sandmeyer reaction of 6-amino-1,8-naphthyridine derivatives via their 6-diaz