78905-28-9Relevant academic research and scientific papers
Studies on Lactams. Part 74. An Approach to the Total Synthesis of Amino Sugars via β-Lactams
Manhas, Maghar S.,Hedge, Vinod R.,Wagle, Dilip R.,Bose, Ajay K.
, p. 2045 - 2050 (2007/10/02)
Convenient intermediates for mono- and di-amino sugars related to antibiotics can be prepared in a stereocontrolled fashion by the rearrangement of 3,4-disubstituted azetidin-2-ones which in turn can be synthesized by stereoselective annelation of certain
N-Unsubstituted β-Lactams from β-Hydroxy-α-amino Acids. Facile Preparation of Intermediates for Isocephalosporins
Bose, Ajay K.,Manhas, M. S.,Vincent, J. E.,Gala, K.,Fernandez, I. F.
, p. 4075 - 4081 (2007/10/02)
A facile method has been devised for the synthesis of N-unsubstituted β-lactams.The cis-azido β-lactam (13) obtained by the reaction of azidoacetyl chloride and the Schiff base (10), derived from cinnamaldehyde and a threonine ester, is subjected to contr
