78934-83-5 Usage
Uses
Used in Research Applications:
SANDOZ 58-035 is used as a research tool for studying the activation of unfolded protein response (UPR) and pattern recognition receptors (PRRs) in mouse peritoneal macrophages. This helps researchers understand the mechanisms and pathways involved in these processes, which can be useful in developing new therapeutic strategies for various diseases and conditions.
Used in Pharmaceutical Industry:
SANDOZ 58-035 may have potential applications in the pharmaceutical industry for the development of drugs that target the unfolded protein response (UPR) and pattern recognition receptors (PRRs) pathways. By modulating these pathways, it may be possible to develop treatments for various diseases and conditions, such as inflammatory disorders, autoimmune diseases, and cancer.
Biochem/physiol Actions
Sandoz 58-035 inhibits the accumulation of cholesteryl esters and inhibits the esterification of cholesterol by 95% in arterial smooth muscle cells in culture.1 It does not affect the triglyceride metabolism by the gut.2
Check Digit Verification of cas no
The CAS Registry Mumber 78934-83-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,9,3 and 4 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 78934-83:
(7*7)+(6*8)+(5*9)+(4*3)+(3*4)+(2*8)+(1*3)=185
185 % 10 = 5
So 78934-83-5 is a valid CAS Registry Number.
InChI:InChI=1/C30H47NOSi/c1-5-6-7-8-9-10-11-15-23-33(3,4)24-22-30(32)31-29(28-16-13-12-14-17-28)25-27-20-18-26(2)19-21-27/h12-14,16-21,29H,5-11,15,22-25H2,1-4H3,(H,31,32)
78934-83-5Relevant academic research and scientific papers
Silicon-bearing amides
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, (2008/06/13)
Compounds of the formula I: STR1 wherein each of R1, R2 and R3 is, independently, (a) alkyl having from 1 to 22 carbon atoms; or (b) of the formula STR2 in which m is 0, 1 or 2, and each R' and R" is independently a hydrogen atom, alkyl having from 1 to 3 carbon atoms, alkoxy having from 1 to 3 carbon atoms, or halo having an atomic weight of from about 19 to 127; and R is of an aralkyl-, phenyl- tryptophanyl- or benzo-cycloalkyl-type, are obtained by hydrogenating corresponding α-β ethylenically-unsaturated analogs (II), which in turn are obtained by hydrogenating corresponding α-β acetylenically-unsaturated analogs. Compounds I and II are useful as anti-atheroslerotic agents.
