78946-56-2Relevant academic research and scientific papers
SYNTHESIS OF 5-AMINO-4-CHLORO-4,5-DIHYDROISOXAZOLES AND 4-CHLOROISOXAZOLES.
Barluenga, Jose,Tomas, Miguel,Lopez, Luis Angel,Jardon, Jesus,Gotor, Vicente
, p. 1763 - 1774 (2007/10/02)
4-Chloro-4,5-dihydroisoxazoles (4) and (5) and -isoxazoles (6) were prepared by reaction of chlorodiimines (1) and (2) with hydroxylamine hydrochloride.Basic treatment of (5) gave rise to N-N bond formation yielding pyrazoles (8).
An Unambiguous Synthesis of Pyrazoles by Sulphur Extrusion from 1,2,6-Thiadiazines
Barluenga, Jose,Lopez-Ortiz, J. Francisco,Tomas, Miguel,Gotor, Vicente
, p. 1891 - 1895 (2007/10/02)
Di-imines (1) react with thionyl chloride and sulphur monochloride and dichloride giving different 1,2,6-thiadiazine S-oxides (3) and 1,2,6-thiadiazines (4), respectively.These last two compounds lead, by heating, to pyrazoles (6) via thermal extrusion of
