78949-95-8
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Basic information
- Product Name: 22-NBD CHOLESTEROL
- Synonyms: N-(7-nitrobenz-2-oxa-1,3-diazole)-23,24-dinor-5-cholen-22-amine-3beta-ol;NBD cholesterol [22-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)aMino)-23,24-bisnor-5-cholen-3b-ol];NBD cholesterol, 90%
- CAS NO:78949-95-8
- Molecular Formula: C28H38N4O4
- Molecular Weight: 494.62572
- EINECS: N/A
- Product Categories: N/A
- Mol File: 78949-95-8.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 650.5°Cat760mmHg
- Flash Point: 347.2°C
- Appearance: /
- Density: 1.27g/cm3
- Vapor Pressure: 8.28E-18mmHg at 25°C
- Refractive Index: 1.622
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 15.03±0.70(Predicted)
- CAS DataBase Reference: 22-NBD CHOLESTEROL(CAS DataBase Reference)
- NIST Chemistry Reference: 22-NBD CHOLESTEROL(78949-95-8)
- EPA Substance Registry System: 22-NBD CHOLESTEROL(78949-95-8)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: 22-24/25
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 78949-95-8(Hazardous Substances Data)
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78949-95-8 Usage
Description
22-NBD cholesterol is a fluorescent analog of cholesterol that contains a fluorescent nitrobenzoxadiazole (NBD) group. It has been used in a variety of in vitro and in vivo applications, including analysis of steroid uptake and esterification, intracellular localization and targeting, and metabolism in mammalian and bacterial cells, and intestinal absorption of cholesterol in hamsters. 22-NBD cholesterol displays excitation/emission maxima of 472/540 nm, respectively, when incorporated into 1,2-dimyristoyl-sn-glycero-3-PC (DMPC; ) vesicles. The emission maximum of 22-NBD cholesterol is solvent-dependent and increases as solvent polarity increases.Check Digit Verification of cas no
The CAS Registry Mumber 78949-95-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,9,4 and 9 respectively; the second part has 2 digits, 9 and 5 respectively.Calculate Digit Verification of CAS Registry Number 78949-95:
(7*7)+(6*8)+(5*9)+(4*4)+(3*9)+(2*9)+(1*5)=208
208 % 10 = 8
So 78949-95-8 is a valid CAS Registry Number.
InChI:InChI=1/C28H38N4O4/c1-16(15-29-23-8-9-24(32(34)35)26-25(23)30-36-31-26)20-6-7-21-19-5-4-17-14-18(33)10-12-27(17,2)22(19)11-13-28(20,21)3/h4,8-9,16,18-22,29,33H,5-7,10-15H2,1-3H3/t16-,18+,19+,20-,21+,22+,27+,28-/m1/s1
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78949-95-8Downstream Products
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22-NBD CHOLESTEROL
