78950-05-7

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 4747-13-1 α-methoxystyrene 

Downstream Products

• 83832-95-5 4,4-Bis-(3-methyl-butoxy)-4-phenyl-butyric acid ethyl ester 
• 6270-17-3 ethyl 3-benzoylpropanoate 
• 83832-43-3 ethyl 4,4-dimethoxy-4-phenylbutanoate 
• 344304-59-2 2-methoxy-2-phenylcyclopropanemethanol 
• 83832-42-2 ethyl 4-methoxy-4-phenyl-3-butenoate 
• 83832-42-2 ethyl 4-methoxy-4-phenyl-3-butenoate 
• 344304-26-3 allyl 2-methoxy-2-phenylcyclopropanecarboxylate 
• 83833-07-2 4-methoxy-4-phenyl-3-buten-1-ol 
• 83833-07-2 4-methoxy-4-phenyl-3-buten-1-ol 
• 83833-04-9 ethyl 2-allyl-4-(3-methyl-1-butoxy)-4-phenyl-3-butenoate 
• 84989-75-3 (E)-2-Methoxy-2-phenylcyclopropancarbonsaeure 
• 84989-75-3 (Z)-2-Methoxy-2-phenylcyclopropancarbonsaeure 

Relevant academic research and scientific papers

Application of molecular dynamics technique to identification of products obtained by reaction of ethoxycarbonylcarbene with various substrates with the use of GC-MS method

In reaction of ethoxycarbonylcarbene with various substrates may occur either cyclopropanes formation or its insertion into C-O and C-H bonds. To support the GC-MS identification of the reaction products a method is suggested for interpretation of the gas-chromatographic retention indices (RI) thereof with the use of an expression ΔI - aΔE+b (a0) where ΔI are the experimentally determined differences between RI of the products and reagents, and aΔE are the corresponding differences of the intramolecular vibration and rotation energies estimated by molecular dynamics procedure.

Isomerisation of 2-Alkoxycyclopropanecarboxylic Acids - An Effective Synthesis of 4-Oxo Carboxylic Acids

(Z/E)-2-Alkoxycyclopropanecarboxylic esters 2/3 were prepared from enol ethers 1 and ethyl diazoacetate.The saponification of these esters gives the corresponding (Z/E)-2-alkoxycyclopropanecarboxylic acids 4/5, which show stereomutation in water/methanol.This isomerisation was studied in labelled solvents and interpreted for the example of (E)-2-methoxy-2-phenylcyclopropanecarboxylic acid (5a).On heating in water/methanol the compounds 4/5 are transformed quantitatively into the corresponding 4-oxo carboxylic acids 6.