78950-36-4

Basic information

• Product Name: 3-Aminothiobenzamide
• Synonyms: 3-AMINO-THIOBENZAMIDE;Benzenecarbothioamide, 3-amino- (9CI);3-amino Benzthioamide;3-aminobenzothioamide
• CAS NO: 78950-36-4
• Molecular Formula: C₇H₈N₂S
• Molecular Weight: 152.22
• Product Categories: THIOAMIDE
• Mol File: 78950-36-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 127-131℃
• Boiling Point: 343.4 °C at 760 mmHg
• Flash Point: 161.5 °C
• Appearance: /
• Density: 1.286 g/cm³
• Vapor Pressure: 7.04E-05mmHg at 25°C
• Refractive Index: 1.719
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 12.91±0.29(Predicted)
• Sensitive: Air & Moisture Sensitive
• CAS DataBase Reference: 3-Aminothiobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Aminothiobenzamide(78950-36-4)
• EPA Substance Registry System: 3-Aminothiobenzamide(78950-36-4)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-43-36-22
• Safety Statements: 26-36/37/39-36/37
• Hazardous Substances Data: 78950-36-4(Hazardous Substances Data)

Usage

Description

3-amino Benzthioamide is a synthetic intermediate useful for pharmaceutical synthesis.

InChI:InChI=1/C7H8N2S/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10)

Upstream product

• 2237-30-1 m-cyanoaniline 

Downstream Products

• 250258-66-3 2-{2-[2-(3-amino-phenyl)-thiazol-4-yl]-ethyl}-isoindole-1,3-dione 
• 134811-94-2 2-(3-aminophenyl)-4,5-dimethylthiazole 

Relevant articles and documents

Histamine H1 receptor ligands. Part I. Novel thiazol-4-ylethanamine derivatives: Synthesis and in vitro pharmacology

A series of 2-substituted thiazol-4-ylethanamines have been synthesized and tested for their histaminergic H1-receptor activities. The compounds with 2-phenyl substitution, regardless of the different physicochemical properties of the meta-substituents at the phenyl ring, showed weak H1-agonistic activity with pD2 values ranging from 4.35 to 5.36. When the phenyl group was replaced by a benzyl group, the resulting compounds all exhibited weak H1-antagonistic activity (pA2: 4.14-4.82). Copyright (C) 1999 Elsevier Science S.A.