78968-60-2Relevant academic research and scientific papers
THE SYNTHESIS AND CYCLISATIOM OF THIOACYLATED DIAMINOGUANIDINES
Kurzer, Frederic,Secker, Jane L.
, p. 1429 - 1436 (2007/10/02)
The thiobenzoylation of 1,2-diaminoguanidine yields 1-amino-2-thioaroylamidoguanidines which are isolable as their stable hydrazones.They are unaffected by alkalis, but are cyclised by mineral acids, with loss of ammonia, to hydrazones of 2-aryl-5-hydrazino-1,3,4-thiadiazoles, or with elimination of hydrazine, to the appropriate 2-amino-5-aryl-1,3,4-thiadiazoles.The action of acetic anhydride effects the same ring-closures, yielding the corresponding acetylated products. 1,2-Diamino-3-phenylguanidine undergoes a comparable series of reactions.
