78969-38-7

Basic information

• Product Name: (2S,3S)-2-[1-(benzyloxy)methoxy-(2R)-propyl]-3-(hydroxymethyl)oxirane
• Synonyms: (2S,3S)-2-[1-(benzyloxy)methoxy-(2R)-propyl]-3-(hydroxymethyl)oxirane
• CAS NO: 78969-38-7
• Molecular Weight: 252.31
• Mol File: 78969-38-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,3S)-2-[1-(benzyloxy)methoxy-(2R)-propyl]-3-(hydroxymethyl)oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-2-[1-(benzyloxy)methoxy-(2R)-propyl]-3-(hydroxymethyl)oxirane(78969-38-7)
• EPA Substance Registry System: (2S,3S)-2-[1-(benzyloxy)methoxy-(2R)-propyl]-3-(hydroxymethyl)oxirane(78969-38-7)

Safety Data

• Hazardous Substances Data: 78969-38-7(Hazardous Substances Data)

Upstream product

• 144732-83-2 methyl (4S)-5-(benzyloxy)methoxy-4-methyl-2-pentenoate 
• 116021-11-5 (2R)-3-benzyloxymethoxy-2-methylpropionic acid methyl ester 
• 201011-92-9 (2S)-3-(benzyloxy)methoxy-2-methyl-1-propanol 
• 73991-91-0 (R)-3-Benzyloxymethoxy-2-methyl-propionaldehyde 
• 3587-60-8 Benzyloxymethyl chloride 
• 78969-35-4 (4S)-5-(benzyloxy)methoxy-4-methyl-2-penten-1-ol 

Downstream Products

• 144681-71-0 (3R,4R)-5-Benzyloxymethoxy-4-methyl-pentane-1,3-diol 
• 410080-99-8 (4R)-4-(1-(benzyloxy)methoxy-(2R)-propyl)-2,2-dimethyl-1,3-dioxane 
• 144732-84-3 (2S,3S,5S,7R,8R,9S)-7-(2-Hydroxy-ethyl)-3-(4-methoxy-benzyloxy)-4,4,8-trimethyl-2-vinyl-1,6-dioxa-spiro[4.5]decan-9-ol 
• 410538-19-1 (2S,3S,5S,7R,8R)-7-(2-Hydroxy-ethyl)-3-(4-methoxy-benzyloxy)-4,4,8-trimethyl-2-vinyl-1,6-dioxa-spiro[4.5]decan-9-ol 
• 144681-74-3 (2R,3S,5S,7R,8S,9S)-9-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4,4,8-trimethyl-7-(2-triethylsilanyloxy-ethyl)-1,6-dioxa-spiro[4.5]decane-2-carbaldehyde 

Relevant articles and documents

Applications of crotyldiisopinocampheylboranes in synthesis: A formal total synthesis of (+)-calyculin A

The formal total synthesis of the marine metabolite (+)-calyculin A is reported. The key steps involve (i) the use of Brown allylboration chemistry to control the relative and absolute stereochemistry of homoallylic alcohol arrays, thus setting eight of the desired stereocenters; (ii) Stille coupling methodology in the construction of the cyano tetraene unit of the natural product; and (iii) a modified Cornforth-Meyers approach to the synthesis of the oxazole fragment.