78987-51-6

Basic information

• Product Name: Benzoic acid, 2-hydroxy-4-nitro-, ethyl ester
• CAS NO: 78987-51-6
• Molecular Formula: C9H9NO5
• Molecular Weight: 211.174
• Mol File: 78987-51-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-hydroxy-4-nitro-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-hydroxy-4-nitro-, ethyl ester(78987-51-6)
• EPA Substance Registry System: Benzoic acid, 2-hydroxy-4-nitro-, ethyl ester(78987-51-6)

Safety Data

• Hazardous Substances Data: 78987-51-6(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 39614-82-9 2-hydroxy-4-nitrobenzoyl chloride 
• 619-19-2 2-hydroxy-4-nitrobenzoic acid 
• 99-77-4 ethyl 4-nitrobenzoate 

Downstream Products

• 78154-68-4 4-(2-hydroxy-4-nitro-benzoyl)-morpholine 
• 476615-11-9 2-butoxy-4-nitro-benzoic acid ethyl ester 
• 102006-34-8 4-nitro-2-octyloxy-benzoic acid 
• 647016-97-5 2-hydroxy-4-nitro-benzoic acid ethylamide 
• 647016-94-2 2-hydroxy-4-nitro-benzoic acid allylamide 
• 476615-10-8 C₁₂H₁₅NO₅ 
• 112819-96-2 4-nitro-2-(3-piperidino-propoxy)-benzoic acid ethyl ester 
• 78154-69-5 1-(2-hydroxy-4-nitro-benzoyl)-piperidine 
• 476615-18-6 ethyl 2-methoxy-4-nitrobenzoate 
• 114740-85-1 1ξ-[2-(2-ethoxycarbonyl-5-nitro-phenoxy)-ethyl]-1ξ,2r,6c-trimethyl-piperidinium; iodide 
• 102666-72-8 2-[2-(2r,6c-dimethyl-piperidino)-ethoxy]-4-nitro-benzoic acid ethyl ester 
• 109615-77-2 1-[3-(2-ethoxycarbonyl-5-nitro-phenoxy)-propyl]-1-methyl-piperidinium; iodide 
• 109587-69-1 1-[3-(2-ethoxycarbonyl-5-amino-phenoxy)-propyl]-1-methyl-piperidinium; iodide 

Relevant articles and documents

Ruthenium(II)-catalyzed synthesis of hydroxylated arenes with ester as an effective directing group

An unprecedented Ru(II) catalyzed ortho-hydroxylation has been developed for the facile synthesis of a variety of multifunctionalized arenes from easily accessible ethyl benzoates with ester as an efficient directing group. Both the TFA/TFAA cosolvent system and oxidants serve as the critical success factors in this transformation. The reaction demonstrates excellent reactivity, good functional group tolerance, and high yields.

ANESTHETIC COMPOUNDS

In one embodiment the invention provides novel compounds of Formula (I) as well as prodrugs, salts, hydrates, solvates and N-oxides thereof. The invention also provides pharmaceutical compositions that include such compounds as well as methods for making and methods for using such compounds in medical therapy.