79015-67-1Relevant academic research and scientific papers
Preparation of organoaluminum reagents from propargylic bromides and aluminum activated by PbCl2and their regio- And diastereoselective addition to carbonyl derivatives
Guo, Li-Na,Gao, Hongjun,Mayer, Peter,Knochel, Paul
supporting information; experimental part, p. 9829 - 9834 (2010/11/02)
Various propargylic and allenic aluminum reagents have been easily prepared by a direct insertion of aluminum into propargylic bromides in the presence of PbCl2 (1 mol%). These organoaluminum reagents react with carbonyl compounds to afford the
SILANES IN ORGANIC SYNTHESIS. 11. REGIOCONTROLLED SYNTHESIS OF α-HYDROXYMETHYLATED (TRIMETHYLSILYL)ALLENES
Daniels, Rhys G.,Paquette, Leo A.
, p. 1579 - 1582 (2007/10/02)
The organometallic produced by reaction of trimethylsilylpropargyl bromide with aluminium amalgam in anhydrous tetrahydrofuran condenses readily with aldehydes and ketones to give allenic alcohols resulting from coupling α to the trimethylsilyl substituen
