790208-54-7 Usage
Uses
Used in Pharmaceutical Industry:
1H-Inden-1-amine,6-fluoro-2,3-dihydro-,(1R)-(9CI) is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure and stereochemistry allow for the creation of novel drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical field, 1H-Inden-1-amine,6-fluoro-2,3-dihydro-,(1R)-(9CI) serves as a precursor in the synthesis of new agrochemicals. Its specific properties and stereochemistry can contribute to the development of innovative compounds with improved efficacy and selectivity in crop protection.
Used in Organic Chemistry Research:
1H-Inden-1-amine,6-fluoro-2,3-dihydro-,(1R)-(9CI) is utilized as a subject of study in organic chemistry research. Its unique structure and chirality provide opportunities for exploring new synthetic pathways, understanding stereoselective reactions, and discovering novel applications in various chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 790208-54-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,0,2,0 and 8 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 790208-54:
(8*7)+(7*9)+(6*0)+(5*2)+(4*0)+(3*8)+(2*5)+(1*4)=167
167 % 10 = 7
So 790208-54-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H10FN/c10-7-3-1-6-2-4-9(11)8(6)5-7/h1,3,5,9H,2,4,11H2/t9-/m1/s1
790208-54-7Relevant academic research and scientific papers
Mapping the substrate scope of monoamine oxidase (MAO-N) as a synthetic tool for the enantioselective synthesis of chiral amines
Herter, Susanne,Medina, Florian,Wagschal, Simon,Benha?m, Cyril,Leipold, Friedemann,Turner, Nicholas J.
, p. 1338 - 1346 (2017/10/06)
A library of 132 racemic chiral amines (α-substituted methylbenzylamines, benzhydrylamines, 1,2,3,4-tetrahydronaphthylamines (THNs), indanylamines, allylic and homoallylic amines, propargyl amines) was screened against the most versatile monoamine oxidase (MAO-N) variants D5, D9 and D11. MAO-N D9 exhibited the highest activity for most substrates and was applied to the deracemisation of a comprehensive set of selected primary amines. In all cases, excellent enantioselectivity was achieved (e.e. >99%) with moderate to good yields (55–80%). Conditions for the deracemisation of primary amines using a MAO-N/borane system were further optimised using THN as a template addressing substrate load, nature of the enzyme preparation, buffer systems, borane sources, and organic co-solvents.
INHIBITOR OF JAK1 AND JAK2
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Page/Page column 12, (2014/01/08)
The present invention provides an amino pyrazole compound, which is 3-[(lR)-6-fluoro-2,3-dihydro-1H-inden-l-yl]-N-(3- methyl-IH- pyrazol-5-yl)-3H-imidazo[4,5-b]pyridin-5-amine, or a pharmaceutically acceptable salt thereof, that inhibits JAK1 and JAK2 and, therefore may be useful in treating cancer.
