79026-62-3

Upstream product

• 1260218-94-7 (2'S,3'R,3S)-5-benzyl-3-isopropyl-2-(2',4'-dimethyl-3'-hydroxy)pentanoyl-1,2,5-thiadiazolidine 1,1-dioxide 
• 1020850-66-1 (4R)-4-(phenyldifluoromethyl)-N-(2S,3R)-(3-hydroxy-2,4-dimethyl-pentanoyl)-1,3-oxazolidin-2-one 

Relevant academic research and scientific papers

Cyclosulfamide as a chiral auxiliary: Application to efficient asymmetric synthesis (alkylation/aldolization)

The chiral cyclosulfamide (S)-2-benzyl-4-isopropyl-1,2,5-thiadiazolidine 1,1-dioxide was designed as a chimera of Evans and Oppolzer chiral auxiliaries. The N-propionyl derivative appeared to be very powerful for the stereocontrolled synthesis of chiral building blocks through asymmetric aldolization and alkylation reactions.

Synthesis of a new fluorinated oxazolidinone and its reactivity as a chiral auxiliary in Aldol reactions

A new enantiomerically pure fluorinated oxazolidinone has been prepared from a fluorinated imidoyl chloride and an optically pure sulfoxide. The diastereoselective reduction of the β-iminosulfoxide thus formed followed by elimination of the sulfoxide and