790294-90-5Relevant articles and documents
Asymmetric oxidation of 3-alkyl-1,2-cyclopentanediones. Part 3: Oxidative ring cleavage of 3-hydroxyethyl-1,2-cyclopentanediones: Synthesis of α-hydroxy-γ-lactone acids and spiro-γ-dilactones
Paju, Anne,Kanger, Tonis,Niitsoo, Olivia,Pehk, Tonis,Mueuerisepp, Aleksander-Mati,Lopp, Margus
, p. 2393 - 2399 (2003)
A Ti(OiPr)4/diethyl tartrate/tBuOOH complex oxidizes 3-hydroxyethyl-1,2-cyclopentanediones, resulting in hydroxylated/ring cleavage products - lactone acids of high enantioselectivity (up to 95% ee) with good yields (up to 75%). These compounds are converted into chiral spiro-γ-dilactones in good yield.