790689-64-4Relevant academic research and scientific papers
Diastereoselective cyclization of γ-δ epoxyketones with (-)-phenylglycinol: Synthesis of both enantiomers of cis-5-alkyl-2-hydroxymethyl pyrrolidines
Andrés, José M.,Herráiz, Ignacio,Pedrosa, Rafael,Pérez-Encabo, Alfonso
, p. 2016 - 2018 (2007/10/03)
A novel condensation of (-)-phenylglycinol with γ,δ- epoxyketones is reported for the preparation of both enantiomers of cis-5-alkyl-2-hydroxymethyl pyrrolidines. The required epoxy-derivatives were easily prepared by epoxidation of the corresponding γ,δ-
