79080-43-6Relevant academic research and scientific papers
Asymmetric Synthesis of a β-Ketol Moiety via 3,5-Disubstitute Isoxazoles: Application to (+)-(S)--Gingerol
Giovanni, Baraldi Pier,Fabio, Moroder,Piero, Pollini Gian,Daniele, Simoni,Achille, Barco,Simonetta, Benetti
, p. 2983 - 2988 (2007/10/02)
A new synthesis of (+/-)--gingerol (13), (+)-(S)--gingerol, and (+)-methyl--gingerol (12c) using 3,5-disubstituted isoxazoles as masked β-ketols, is described.Reductive fission of the labile N-O bond of the isoxazoles (8a) and (8b) gave the enami
