79098-72-9

Basic information

• Product Name: 1-<2-hydroxy-2-(3,4,5-trimethoxyphenyl)-1-methylethyl>-4-(octahydro-2-H-benzimidazol-2-one-1-yl)piperidine
• Synonyms: 1-<2-hydroxy-2-(3,4,5-trimethoxyphenyl)-1-methylethyl>-4-(octahydro-2-H-benzimidazol-2-one-1-yl)piperidine
• CAS NO: 79098-72-9
• Molecular Weight: 447.575
• Mol File: 79098-72-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-<2-hydroxy-2-(3,4,5-trimethoxyphenyl)-1-methylethyl>-4-(octahydro-2-H-benzimidazol-2-one-1-yl)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-<2-hydroxy-2-(3,4,5-trimethoxyphenyl)-1-methylethyl>-4-(octahydro-2-H-benzimidazol-2-one-1-yl)piperidine(79098-72-9)
• EPA Substance Registry System: 1-<2-hydroxy-2-(3,4,5-trimethoxyphenyl)-1-methylethyl>-4-(octahydro-2-H-benzimidazol-2-one-1-yl)piperidine(79098-72-9)

Safety Data

• Hazardous Substances Data: 79098-72-9(Hazardous Substances Data)

Upstream product

• 79098-86-5 cis-(+/-)-1-piperidin-4-yl-octahydro-2H-benzoimidazol-2-one hydrochloride 
• 6961-12-2 1-(4-piperidinyl)-1,3-dihydro-2-oxo-benzimidazole hidrochloride 
• 52190-29-1 2-bromo-1-(3,4,5-trimethoxyphenyl)propan-1-one 
• 79098-66-1 (3aR,7aR)-1-{1-[1-Methyl-2-oxo-2-(3,4,5-trimethoxy-phenyl)-ethyl]-piperidin-4-yl}-octahydro-benzoimidazol-2-one 
• 79098-66-1 (3aS,7aR)-1-{1-[1-Methyl-2-oxo-2-(3,4,5-trimethoxy-phenyl)-ethyl]-piperidin-4-yl}-octahydro-benzoimidazol-2-one 
• 20662-53-7 4-(2-keto-1-benzimidazolinyl)piperidine 
• 74179-07-0 1-<2-oxo-2-(3,4,5-trimethoxyphenyl)-1-methylethyl>-4-(1,3-dihydro-2H-benzimidazol-2-one-1-yl)piperidine 

Relevant articles and documents

New antihypertensive agents. III. Synthesis and antihypertensive activity of some arylalkyl piperidines carrying a heterocycle at the 4-position

We synthesized a series of arylalkyl piperidines (II) carrying a heterocycle at the 4-position of piperidine and examined the hypotensive activities of the products. Compound 23 had the highest hypotensive activity in anesthetized normotensive rats (-78mmHg, 30 mg/kg, i.p.) and compound 12 showed the strongest hypotensive activity (-95 mmHg, 30 mg/kg, p.o.) in unanesthetized spontaneously hypertensive rats. Only compound 16 produced a considerable decrease in blood pressure in both animal models.