79102-28-6Relevant academic research and scientific papers
Ring Opening of Aziridines by Different Fluorinating Reagents: Three Synthetic Routes to α,β-Fluoro Amines with Different Stereochemical Pathways
Alvernhe, Gerald M.,Ennakoua, Christine M.,Lacombe, Sylvie M.,Laurent, Andre J.
, p. 4938 - 4948 (2007/10/02)
The syntheses of α,β-fluoro amines from the reaction of secondary aziridines with either Olah's reagent (HF, pyridine) or anhydrous hydrogen fluoride and of N-activated aziridines with partially neutralized Olah's reagent (NR3-nHF) are reported.The stereo
SYNTHESE D'α,β-FLUOROAMINES A PARTIR D'AZIRIDINES: ORIENTATION DE L'OUVERTURE DU CYCLE ET AMELIORATION DU POUVOIR FLUORANT DU REACTIF DE OLAH
Alvernhe, Gerard,Lacombe, Sylvie,Laurent, Andre
, p. 289 - 292 (2007/10/02)
Ring opening of aliphatic and aromatic aziridines by addition of Olah's reagent has ben studied.Yields and regioselectivity are improved when using the corresponding N-activated aziridines and less acidic fluorinating reagents obtained by addition of trie
