791061-65-9

Basic information

• Product Name: (5R)-N-(1-ethyl-1-phenylpropyl)-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide
• Synonyms: (5R)-N-(1-ethyl-1-phenylpropyl)-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide
• CAS NO: 791061-65-9
• Molecular Weight: 430.593
• Mol File: 791061-65-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5R)-N-(1-ethyl-1-phenylpropyl)-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (5R)-N-(1-ethyl-1-phenylpropyl)-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide(791061-65-9)
• EPA Substance Registry System: (5R)-N-(1-ethyl-1-phenylpropyl)-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide(791061-65-9)

Safety Data

• Hazardous Substances Data: 791061-65-9(Hazardous Substances Data)

Upstream product

• 667920-89-0 ethyl 2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 1293345-01-3 ethyl (5R)-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 667930-86-1 (5R)-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylic acid 
• 104177-96-0 α,α-diethylbenzylamine hydrochloride 
• 1207507-51-4 C₁₈H₂₁N₃O₂ 
• 5650-07-7 3-methyl-1-phenyl-but-2-en-1-one 
• 23286-70-6 5-amino-3-methyl-1H-pyrazole-4-carboxylic acid ethyl ester 

Relevant articles and documents

Novel and potent calcium-sensing receptor antagonists: Discovery of (5R)-N-[1-ethyl-1-(4-ethylphenyl)propyl]-2,7,7-trimethyl-5-phenyl-4,5,6, 7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide monotosylate (TAK-075) as an orally active bone anabolic agent

The calcium-sensing receptor antagonist (CaSR) has been recognized as a promising target of anabolic agents for treating osteoporosis. In the course of developing a new drug candidate for osteoporosis, we found tetrahydropyrazolopyrimidine derivative 1 to