791084-51-0

Basic information

• Product Name: methyl 5-O-(tert-butyldiphenylsilyl)-2-deoxy-α,β-D-threo-pentofuranoside
• Synonyms: methyl 5-O-(tert-butyldiphenylsilyl)-2-deoxy-α,β-D-threo-pentofuranoside
• CAS NO: 791084-51-0
• Molecular Weight: 386.563
• Mol File: 791084-51-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 5-O-(tert-butyldiphenylsilyl)-2-deoxy-α,β-D-threo-pentofuranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-O-(tert-butyldiphenylsilyl)-2-deoxy-α,β-D-threo-pentofuranoside(791084-51-0)
• EPA Substance Registry System: methyl 5-O-(tert-butyldiphenylsilyl)-2-deoxy-α,β-D-threo-pentofuranoside(791084-51-0)

Safety Data

• Hazardous Substances Data: 791084-51-0(Hazardous Substances Data)

Upstream product

• 159423-78-6 (2R,3R)-1-(tert-Butyl-diphenyl-silanyloxy)-5,5-dimethoxy-pentane-2,3-diol 
• 33639-45-1 3-butynal dimethyl acetal 
• 114071-58-8 methyl 3,5-O-isopropylidene-2-O-<(methylthio)-thiocarbonyl>-αβ-D-xylofuranoside 
• 116195-62-1 methyl 2-deoxy-3,5-O-isopropylidene-αβ-D-threo-pentofuranoside 
• 112245-59-7 methyl 3,5-O-isopropylidene-αβ-D-xylofuranoside 
• 40156-61-4 5,5-dimethoxy-pent-2t-en-1-ol 
• 79576-62-8 5-hydroxy-pent-3-ynal-dimethylacetal 
• 863396-37-6 methyl 2-deoxy-αβ-D-threo-pentofuranoside 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 159423-76-4 tert-Butyl-((E)-5,5-dimethoxy-pent-2-enyloxy)-diphenyl-silane 

Downstream Products

• 66323-40-8 alpha-3'-azido-2',3'-dideoxythymidine 
• 133908-22-2 methyl 3-azido-5-O-tert-butyldiphenylsilyl-2,3-dideoxy-α,β-D-erythor-pentofuranoside 
• 30516-87-1 3'-azido-2',3'-deoxythymidine 
• 114071-61-3 Trifluoro-methanesulfonic acid (2R,3R)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methoxy-tetrahydro-furan-3-yl ester 

Relevant articles and documents

Asymmetric synthesis of carbohydrates: Synthesis of 2-deoxy-D- and 2-deoxy-L-xylofuranosides from a simple achiral precursor

The acetylenic alcohol, 3, readily prepared in two steps from propargyl bromide, 1, is converted to methyl 2-deoxy-D-xylofuranoside, 13, and to the unnatural L-enantiomer, 12, in 5 steps and 50% overall yield, utilizing asymmetric dihydroxylation (AD) of alkene 7 for introduction of chirality. A similar strategy from the isomeric Z-allylic alcohol, 4, afforded the 2-deoxy-L-ribofuranoside, but in modest enantiomeric excess.