791101-22-9Relevant academic research and scientific papers
Preparation of vinyl ethers using a Wittig approach, and their subsequent hydrogenation employing continuous-flow processing
Balti, Monaem,Efrit, Mohamed Lotfi,Leadbeater, Nicholas E.
supporting information, p. 1804 - 1806 (2016/04/05)
A methodology is reported for the preparation of various aromatic-functionalized vinyl ethers using a Wittig approach. The subsequent hydrogenation of the vinyl ether products to their saturated analogs is also performed and is streamlined by employing continuous-flow processing.
Total synthesis of catenioblin B
Srinivas, Theegala,Hügel, Helmut M.,Radha Krishna, Palakodety
, p. 5952 - 5954 (2014/12/12)
Herein we report the first total synthesis of catenioblin B (1) via a titanium(IV) mediated regioselective epoxide ring-opening, Grignard reaction, Luche's reduction and TEMPO/BAIB mediated intramolecular cyclization as the key steps.
Discovery of a potent, metabolically stabilized resorcylic lactone as an anti-inflammatory lead
Du,Matsushima,Spyvee,Goto,Shirota,Gusovsky,Chiba,Kotake,Yoneda,Eguchi,DiPietro,Harmange,Gilbert,Li,Davis,Jiang,Zhang,Pelletier,Wong,Sakurai,Yang,Ito-Igarashi,Kimura,Kuboi,Mizui,Tanaka,Ikemori-Kawada,Kawakami,Inoue,Kawai,Kishi,Wang
supporting information; scheme or table, p. 6196 - 6199 (2010/06/19)
With bioactivity-guided phenotype screenings, a potent anti-inflammatory compound f152A1 has been isolated, characterized and identified as the known natural product LL-Z1640-2. Metabolic instability precluded its use for the study on animal disease model
MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS
-
Page/Page column 96-97, (2010/02/07)
The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R1 -R11, t, X, Y, Z, and n are as defined herein.
