79152-68-4Relevant academic research and scientific papers
Enantioselective activation of aldehydes by chiral phosphoric acid catalysts in an aza-ene-type reaction between glyoxylate and enecarbamate
Terada, Masahiro,Soga, Kazuyo,Momiyama, Norie
supporting information; experimental part, p. 4122 - 4125 (2009/03/12)
(Chemical Equation Presented) Double interaction doesit: Highly enantio- and diastereoselective aza-ene-type reaction of glyoxylate with an enecarbamate is accomplished by using a binol-derived phosphoric acid catalyst (see scheme). DFT computational analysis revealed that two hydrogen bonds formed between the catalyst and the aldehyde are critical for the high enantioselectivity.
