791609-47-7

Upstream product

• 54503-64-9 2,3-O-isopropylidene-5-O-trityl-D-ribofuranose 
• 791609-49-9 5,6-dimethyl-2,3-dihydro-1H-indole 
• 858244-30-1 N-(2,4,5-trimethylphenyl)formamide 
• 30877-30-6 5,6-dimethyl-indole 
• 912561-27-4 5,6-dimethyl-1-trimethylsilanyl-2,3-dihydro-1H-indole 

Downstream Products

• 791609-51-3 1-((3aR,4S,6R,6aR)-2,2-Dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-5,6-dimethyl-1H-indole 

Relevant academic research and scientific papers

Regioselective glycosylation: Synthesis of α-indoline nucleosides

Novel indoline ribonucleosides with the α-N-glycoside configuration are synthesized with very high regioselectivity in 90-96% yield, using TMS protected indolines and 2,3-O-(1-methylethylidene)-5-O-(triphenylmethyl)- α/β-D-ribofuranose. The structures of

Direct glycosylation: Synthesis of α-indoline ribonucleosides

A selective synthesis of α-anomers of indoline nucleosides is described. Ribonucleosides of indoline, dimethylindoline and 5-bromoindoline are readily prepared in good yield by reacting indoline bases directly with the protected sugar, 2,3-O-(1-methylethylidene) 5-O-(triphenylmethyl)-D-ribofuranose in dry ethanol or methylene chloride in presence of molecular sieves at 40-60°C.