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Usage

Uses

Used in Pharmaceutical Industry:
(R)-(-)-3,3'-BIS(TRIPHENYLSILYL)-1,1'-BINAPHTHYL-2,2'-DIYL HYDROGENPHOSPHATE, 95% is used as an organocatalyst for the first enantioselective organocatalytic reductive amination reaction. This reaction is essential for the synthesis of chiral amines, which are key building blocks in the production of various pharmaceuticals and agrochemicals. The use of this catalyst allows for the efficient and selective synthesis of these chiral compounds, improving the overall yield and purity of the final product.
Used in Chemical Research:
In the field of chemical research, (R)-(-)-3,3'-BIS(TRIPHENYLSILYL)-1,1'-BINAPHTHYL-2,2'-DIYL HYDROGENPHOSPHATE, 95% serves as a valuable tool for studying enantioselective reactions and developing new synthetic methodologies. Its unique structural features and high catalytic activity make it an attractive candidate for exploring novel reaction pathways and expanding the scope of asymmetric synthesis.
Used in Fine Chemicals Industry:
(R)-(-)-3,3'-BIS(TRIPHENYLSILYL)-1,1'-BINAPHTHYL-2,2'-DIYL HYDROGENPHOSPHATE, 95% is also utilized in the fine chemicals industry for the production of enantiomerically pure compounds with high added value. These compounds are often used as intermediates in the synthesis of specialty chemicals, fragrances, and flavors, where the absolute configuration of the chiral center is critical for the desired properties and performance of the final product.
Overall, (R)-(-)-3,3'-BIS(TRIPHENYLSILYL)-1,1'-BINAPHTHYL-2,2'-DIYL HYDROGENPHOSPHATE, 95% is a versatile and highly effective organocatalyst with a wide range of applications across various industries, including pharmaceuticals, chemical research, and fine chemicals. Its ability to promote enantioselective reactions and facilitate the synthesis of chiral compounds makes it an indispensable tool in the field of asymmetric synthesis.

Reaction

A chiral phosphoric acid catalyst providing a convenient strategy for the enantioselective construction of protected primary amines and a highly stereoselective method for the reductive amination of heterocyclic amines. Chiral phosphoric acid used for the enantioselective Biginelli and Biginelli-like reactions. Chiral phosphoric acid organocatalyst used in the asymmetric, three-component Povarov reaction involving 2-hydroxystyrenes. An efficient method to access structurally diverse cis-disubstituted tetrahydroquinolines in high stereoselectivities of up to >99:1 dr and 97% ee. A gold/chiral phosphoric acid catalyst used for the highly stereoselective, three-component reaction of salicylaldehydes, anilines, and alkynols to give aromatic spiroacetals in high yields and stereoselectivities. The first highly enantioselective catalytic protocol for the reductive coupling of ketones and hydrozones. Reagent-controlled regioselectivity enabled by dual activation.