791616-68-7

Basic information

• Product Name: R-3,3'-bis(4-nitrophenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate
• Synonyms: R-3,3'-bis(4-nitrophenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate;(R)-4-Oxide-2,6-bis[4-(4-nitrophenyl)--8,9,10,11,12,13,14,15-octahydro-4-hydroxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin;(11bR)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-2,6-bis(4-nitrophenyl)-4-oxide-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin;(11bR)-8,9,10,11,12,13,14,15-Octahydro-4-hydroxy-2,6-bi s(4-nitrophenyl)-4-oxide-dinaphtho[2,1-d:1',2'-f][1,3,2]dio xaphosphepin,99%e.e.
• CAS NO: 791616-68-7
• Molecular Formula: C32H28N2O8P
• Molecular Weight: 599.547081
• Mol File: 791616-68-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 836.8±75.0 °C(Predicted)
• Appearance: /
• Density: 1.51±0.1 g/cm3(Predicted)
• PKA: 1.09±0.20(Predicted)
• CAS DataBase Reference: R-3,3'-bis(4-nitrophenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate(CAS DataBase Reference)
• NIST Chemistry Reference: R-3,3'-bis(4-nitrophenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate(791616-68-7)
• EPA Substance Registry System: R-3,3'-bis(4-nitrophenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate(791616-68-7)

Safety Data

• Hazardous Substances Data: 791616-68-7(Hazardous Substances Data)

Upstream product

• 39648-74-3 (Ra)-5,6,7,8,5',6',7',8'-octahydro-[1,1']binaphthalenyl-2,2'-diol 
• 18531-94-7 (R)-1,1'-Bi-2-naphthol 
• 2129645-35-6 (R)-2,2'-dihydroxy-3,3'-bis(4-nitrophenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-dinaphthyl 

Relevant articles and documents

Chiral 3-substituted isoindolinone compounds, and preparation method and application thereof

The invention discloses chiral 3-substituted isoindolinone compounds, and a preparation method and application thereof. The compounds are as shown in a formula I which is described in the specification. The preparation method comprises a step of subjecting a compound as shown in a formula II and a compound as shown in a formula III to a Ugi two-component four-center reaction or subjecting a compound as shown in a formula IV, a compound as shown in a formula V and the compound as shown in the formula III to a Ugi three-component four-center reaction in the presence of a chiral phosphoric acid catalyst so as to obtain the compounds as shown in the formula I after completion of the reactions. According to the invention, extensively available raw materials and the cheap and easily available chiral catalyst are used; the raw materials are subjected to the Ugi two-component four-center reaction or the Ugi three-component four-center reaction so as to efficiently prepare the chiral 3-substituted isoindolinone compounds in one step; reaction conditions are mild; and the prepared compounds are stable in the air, high in yield, good in enantioselectivity and easy to separate and purify, and have good application prospects.