791618-20-7Relevant academic research and scientific papers
A versatile strategy to synthesize: N -methyl-anthranilic acid-labelled glycoprobes for fluorescence-based screening assays
Bertin-Jung, Isabelle,Bui, Catherine,Fournel-Gigleux, Sylvie,Gulberti, Sandrine,Jacquinet, Jean-Claude,Lopin-Bon, Chrystel,Ouzzine, Mohamed,Ramalanjaona, Nick,Robert, Anne,Vincourt, Jean-Baptiste
supporting information, p. 10746 - 10749 (2020/10/02)
Here we propose a general strategy to label carbohydrates with N-methyl-anthranilic acid at the anomeric position. Through two examples, we demonstrate that the generated glycoprobes are suitable for fluorescence-based binding/competition assays. Our approach is expected to readily generate series of glycoprobes dedicated to screening assays for the discovery of drugs targeting carbohydrate-protein interactions.
Efficient preparation of glycoclusters from silsesquioxanes
Gao, Yongjun,Eguchi, Atsuko,Kakehi, Kazuaki,Lee, Yuan C.
, p. 3457 - 3460 (2007/10/03)
(Chemical Equation Presented) A new type of glycocluster based on polyhedral oligosilsesquioxanes (POSS) has been efficiently prepared from unprotected mannoside and lactoside employing a convergent approach of thiol-radical addition reaction. The versatility of this approach was demonstrated by functionalization of mannosides and lactosides of different-length spacers.
