79206-22-7 Usage
Uses
Used in Pharmaceutical Industry:
N-Dodecyldeoxynojirimycin is used as a therapeutic agent for the treatment of various diseases, such as lysosomal storage disorders and cancer. Its ability to inhibit specific glucosidases can help regulate the activity of these enzymes and prevent the accumulation of undegraded substrates in cells.
Used in Research Applications:
N-Dodecyldeoxynojirimycin is used as a research tool to study the function and regulation of glucosidases in biological systems. Its selective inhibition of these enzymes can provide valuable insights into their role in cellular processes and disease mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 79206-22-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,2,0 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 79206-22:
(7*7)+(6*9)+(5*2)+(4*0)+(3*6)+(2*2)+(1*2)=137
137 % 10 = 7
So 79206-22-7 is a valid CAS Registry Number.
InChI:InChI=1/C18H37NO4/c1-2-3-4-5-6-7-8-9-10-11-12-19-13-16(21)18(23)17(22)15(19)14-20/h15-18,20-23H,2-14H2,1H3/t15?,16?,17-,18-/m1/s1
79206-22-7Relevant academic research and scientific papers
Baxter,Reitz
, p. 3175 - 3185 (1994)
Polyhydroxylated pyrrolidines and piperidines were prepared by the double reductive amination of dicarbonyl sugars with primary amines and NaCNBH3 in MeOH. Stereocontrol in these reactions depended on the nature of the amine and dicarbonyl sugar. For example, 5-keto-D-fructose (7) gave three pyrrolidine stereoisomers, with the N-alkylated 2,5-anhydro-2,5-imino-D-glucitol predominating. Under similar reaction conditions with benzhydrylamine, 5-keto-D-glucose (20) afforded a 96:4 mixture of piperidines favoring D-gluco 25A, whereas 5-keto-D-mannose (6) produced a 67:33 mixture enriched in D-manno isomer 40. This method allowed for the direct and relatively short synthesis of 1-deoxynojirimycin (DNJ, 1) and 1-deoxymannojirimycin (DMJ, 5) and N-alkylated derivatives thereof. Similar reactions with O-protected 5-keto-D-glucose derivatives 21 and 22 were less stereoselective and lower yielding.
