79213-60-8

Basic information

• Product Name: 3-chloro-(1,1'-biphenyl)-4-carbaldehyde
• CAS NO: 79213-60-8
• Molecular Weight: 216.667
• Mol File: 79213-60-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-chloro-(1,1'-biphenyl)-4-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-(1,1'-biphenyl)-4-carbaldehyde(79213-60-8)
• EPA Substance Registry System: 3-chloro-(1,1'-biphenyl)-4-carbaldehyde(79213-60-8)

Safety Data

• Hazardous Substances Data: 79213-60-8(Hazardous Substances Data)

Upstream product

• 158435-41-7 4-bromo-2-chlorobenzaldehyde 
• 98-80-6 phenylboronic acid 
• 179754-00-8 trifluoromethanesulfonic acid 3-chloro-4-formylphenyl ester 
• 56962-11-9 2-chloro-4-hydroxybenzaldehyde 

Relevant articles and documents

austria takes charge of his Wei derivative and its preparation method and application

The invention relates to an oseltamivir derivative as well as a preparation method and application thereof. The compound has the structure shown in a formula I. The invention provides an efficient influenza virus neuraminidase inhibitor with high selectivity, which is used for preparing drugs for preventing or curing flu, particularly the diseases caused by N1 influenza virus. The invention also relates to a drug composition comprising the compound shown in the formula I.

NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME

The present invention provides a novel nitrogen-containing heterocyclic derivative and an organic electronic device using the same. The organic electronic device according to the present invention has excellent properties in terms of efficiency, driving voltage, and a life span.

ERβ ligands. Part 2: Synthesis and structure-activity relationships of a series of 4-hydroxy-biphenyl-carbaldehyde oxime derivatives

A series of biphenyl carbaldehyde oximes (6) was prepared and shown to have significant selectivity for the estrogen receptor-β (ERβ). The exploitation of the oxime moiety as a hydrogen bond donating group, which mimicked the C-ring of genistein makes these compounds unique. Molecular modeling studies showed the oxime moiety hydrogen bonding to the histidine residue, which was supported by the structure-activity relationships. The most potent compounds in this study had IC50 values in a radioligand binding assay of between 8-35nM. Among the most selective compounds were 6i and 6s (49- and 31-fold ERβ selective, respectively).