79232-62-5Relevant articles and documents
Reactions with Aziridines. XXIV: Amidoethylation of Esters of Monosubstituted Malonic Acids
Budny, Jochen,Stamm, Helmut
, p. 657 - 664 (2007/10/02)
Diethyl phenylmalonate (1a) and methylmalonate (1b) have been amidoethylated with the N-acyl aziridines 3a-e under various conditions.In one case only (5) we were able to isolate the primarily formed amidoethyl derivative as minor product which otherwise cyclized apparently completely to form the corresponding N-acyl pyrrolidones 6a-f which mostly underwent further (alcoholytic) reactions.