79236-59-2Relevant academic research and scientific papers
Highly Ligand Efficient and Selective N-2-(Thioethyl)picolinamide Histone Deacetylase Inhibitors Inspired by the Natural Product PsammaplinA
Baud, Matthias G.J.,Haus, Patricia,Leiser, Thomas,Meyer-Almes, Franz-Josef,Fuchter, Matthew J.
, p. 149 - 156 (2013/03/28)
Novel picolinamide-based histone deacetylase (HDAC) inhibitors were developed, drawing inspiration from the natural product psammaplinA. We found that the HDAC potency and isoform selectivity provided by the oxime unit of psammaplinA could be reproduced b
