79253-37-5

Basic information

• Product Name: (S)-3-(4-(tert-butyl)phenyl)-2-methylpropan-1-ol
• Synonyms: (S)-3-(4-(tert-butyl)phenyl)-2-methylpropan-1-ol
• CAS NO: 79253-37-5
• Molecular Weight: 206.328
• Mol File: 79253-37-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (S)-3-(4-(tert-butyl)phenyl)-2-methylpropan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(4-(tert-butyl)phenyl)-2-methylpropan-1-ol(79253-37-5)
• EPA Substance Registry System: (S)-3-(4-(tert-butyl)phenyl)-2-methylpropan-1-ol(79253-37-5)

Safety Data

• Hazardous Substances Data: 79253-37-5(Hazardous Substances Data)

Upstream product

• 117721-78-5 (E)-3-(4-(tert-butyl)phenyl)-2-methylprop-2-en-1-ol 
• 63488-10-8 4-tert-butylmagnesium bromide 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 18127-01-0 3-(4-tert-butylphenyl)propionaldehyde 
• 939-97-9 4-tert-Butylbenzaldehyde 
• 1425169-39-6 C₂₀H₂₄OS₂ 
• 172477-52-0 2-(4-tert-butylbenzyl)-1,3-propanediol 
• 173379-58-3 (S)-(+)-<2-(4-tert-butylbenzyl)-2-chloromethyl>ethyl acetate 
• 173379-57-2 (R)-(+)-<2-(4-tert-butylbenzyl)-2-hydroxymethyl>ethyl acetate 
• 18880-00-7 1-(bromomethyl)-4-(1,1-dimethylethyl)benzene 
• 37765-76-7 2-(4-tert-butylbenzyl)diethylmalonate 
• 98-51-1 4-tert-butyltoluene 
• 101711-78-8 (3R)-3-propionyl-4-benzyloxazolidin-2-one 
• 180850-14-0 3-(4-tert-butylphenyl)-2-methylprop-2-enal 

Downstream Products

• 76492-90-5 fenpropimorph 
• 80-54-6 p-tert-butyl-α-methylhydrocinnamic aldehyde 
• 138320-32-8 (S)-(+)-2-(4-tert-butylbenzyl)-1-chloropropane 
• 75166-31-3 (R)-(-)-3-(4-tert-Butylphenyl)-2-methylpropanal 

Relevant articles and documents

Enantioselective hydrogenation of olefins with iridium-phosphanodihydrooxazole catalysts

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Highly enantioselective hydrogenation of 2-substituted-2-alkenols catalysed by a ChenPhos-Rh complex

Highly enantioselective hydrogenation of a variety of 2-substituted-2- alkenols has been achieved using a ChenPhos-Rh complex as catalyst, giving ≥99% ee for most substrates. Optically active antifungal agent amorolfine was first synthesised using hydrogenation as the key step. This journal is

Stereoselective cyclopropanation and ring-opening: Application to the synthesis of pure (S)-2-methyl-3-arylpropylamines

Stereoselective catalytic and stoichiometric cyclopropanation of styrenes 3a,3b was studied; the stoichiometric method turned out superior in the terms of enantioselectivity. The intermediate carboxymethyl cyclopropane 11a,11b, obtained on reduction of carbethoxy derivatives 4a,4b, were hydrogenolyzed to (S)-1,3-substituted-2-methylpropanes 15a,15b. The highest conversion and regioselectivity was obtained with 3% Pd/C as the catalyst. The final steps, chlorination of alcohol 15a into 19a, and alkylation of cyclic sec amines were already demonstrated by us (ref. 2c) to afford (S)-(- )-2-(4-tert-butylphenyl)-1-cis-2,6-dimethylmorpholyl)propane (S-1a) and (S)- (-)-2-(4-tert-butylphenyl)-1-piperidylpropane (S-2a), the (S)-enantiomers of two systemic fungicides presently commercialized as racemates, without any lost of enantiomeric purity.