79263-62-0Relevant academic research and scientific papers
Design, synthesis, and anti-Helicobacter pylori activity of erythromycin A (E)-9-oxime ether derivatives
Nam, Ghilsoo,Kang, Tae Won,Shin, Jung Hyu,Choi, Kyung Il
, p. 569 - 572 (2007/10/03)
The synthesis and anti-Helicobacter pylori (H. pylori) activity evaluation of a new series of erythromycin A (E)-9-oxime ether derivatives are described. These compounds exhibited comparable in vitro anti-H. pylori activity and improved acid stability com
Synthese et activite biologique de prodrogues de l'acide oxolinique
Loubinoux, B,Colin, JL,Thomas, V
, p. 461 - 467 (2007/10/02)
Synthesis and biological activities of oxolinic acid pro-drugs.Antiseptic phenols, anti-inflammatory acids and polyethyleneglycol moieties have been attached by labile bonds to oxolinic acid giving pro-drugs with anti-bacterial activities.Some of them are more soluble in water, exhibit a more sustained action in the time and give higher plasma and tissue concentrations compared with the free drug.
UNE NOUVELLE METHODE POUR LA PROTECTION DE LA FONCTION HYDROXYLE
Loubinoux, B.,Coudert, G.,Guillaumet, G.
, p. 1973 - 1976 (2007/10/02)
Reactions of guaiacylmethyl chloride with alcohols afford the corresponding ethers in high yield ; selective protections can be achieved by phase transfer catalysis ; cleavages of the ethers by ZnBr2 are very easy.
