79275-63-1

Upstream product

• 128084-23-1 1-[dimethyl(phenyl)silyl]-3-phenylpropane-1-one 
• 10147-11-2 propargyl benzene 
• 768-33-2 phenyldimethylsilyl chloride 
• 102-93-2 3-phenylpropionamide 
• 673-32-5 1-Phenylprop-1-yne 
• 3839-31-4 dimethyl(phenyl)silyllithium 

Downstream Products

• 615-13-4 2-indanone 
• 79194-28-8 C₂₃H₃₄Si₃ 
• 79194-26-6 1-phenyldimethylsilyl-1-trimethylsilyl-3-phenylpropadiene 
• 79194-27-7 1-dimethylphenylsilyl-1,3-bis(trimethylsilyl)-3-phenylpropyne 
• 79194-25-5 1-dimethylphenylsilyl-3-trimethylsilyl-3-phenylpropyne 

Relevant academic research and scientific papers

Bifunctional Biphenyl-2-ylphosphine Ligand Enables Tandem Gold-Catalyzed Propargylation of Aldehyde and Unexpected Cycloisomerization

Despite extensive studies in gold catalysis, σ-allenylgold species have not been invoked as catalytic intermediates and their reactivities not studied. This work reports for the first time they are generated in situ and undergo nucleophilic addition to activated aldehydes in a bifunctional phosphine ligand-enabled gold catalysis. This development reveals a broad range of opportunities to achieve propargylic C-H functionalization for the first time under catalytic and mild conditions. The homopropargylic alcohols generated undergo ligand-enabled cycloisomerizations involving an unexpected silyl migration.

Ru-Catalyzed Migratory Geminal Semihydrogenation of Internal Alkynes to Terminal Olefins

Semihydrogenation of alkynes to alkenes represents a fundamentally useful transformation. In addition to the well-known cis- and trans-semihydrogenation, herein a geminal semihydrogenation of internal alkynes featuring 1,2-migration is described, which pr

A synthesis of enantiomerically enriched propargyl silanes

Reduction of ethyl 3-methyl-, 3-isopropyl- and 3-n-pentyl-3-[dimethyl(phenyl)silyl]propanoates 4 with DIBAL to the aldehydes 5, enol trifluoromethanesulfonate (triflate) formation using trifluoromethanesulfonic (triflic) anhydride and 2,6-di-tert-butylpyridine, and elimination using LDA, gives the propargyl silanes 8. The esters 4 could also be prepared enantiomerically enriched (11), and the final products are the enantiomerically enriched propargyl (homochiral) silanes 14.

SYNTHESIS AND PHOTOCHEMISTRY OF SILYLPHENYLPROPADIENES AND SILYLPHENYLPROPYNES

The synthesis and photoisomerization of the title compounds are described.Bis (silyl)-3-phenylpropyne yields a -photorearranged product of propadiene type, whereas tris(silyl)-3-phenylpropadiene is photochemically stable; however, a -thermal rea