792909-07-0Relevant academic research and scientific papers
Highly diastereo- and enantioselective reactions of enecarbamates with an aldehyde
Matsubara, Ryosuke,Vital, Paulo,Nakamura, Yoshitaka,Kiyohara, Hiroshi,Kobayashi, Shu
, p. 9769 - 9784 (2004)
Catalytic asymmetric addition reactions of enecarbamates with ethyl glyoxylate have been developed using CuClO4·4CH3CN and a diimine ligand as the catalyst. Highly diastereo- and enantioselective addition reactions of α-mono-substitu
METHOD OF ENANTIOMETRICALLY SELECTIVE NUCLEOPHILIC ADDITION REACTION TO CARBONYL OF ENAMIDE AND METHOD OF SYNTHESIZING OPTICALLY ACTIVE ALPHA-HYDROXY-GAMMA-KETO ACID ESTER AND HYDROXYDIKETONE
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Page/Page column 21-22, (2008/06/13)
A method of an enantioselective nucleophilic addition reaction to carbonyl, which enables an asymmetric synthesis of an optically active α-hydroxy-γ-keto acid ester, an optically active α-hydroxy-γ-amino acid ester, hydroxydiketone compounds, etc. being u
Highly diastereo- and enantioselective reactions of enecarbamates with ethyl glyoxylate to give optically active syn and anti α-alkyl-β- hydroxy imines and ketones
Matsubara, Ryosuke,Nakamura, Yoshitaka,Kobayashi, Shu
, p. 3258 - 3260 (2007/10/03)
The remarkably selective addition of enecarbamates 2 to ethyl glyoxylate (1) in the presence of a copper-dilmine catalyst (0.1 mol%) gives the corresponding imines 3 in high yields with excellent enantioselectivities. A concerted aza-enetype reaction mech
