79294-57-8Relevant articles and documents
Amphipathic benzoic acid derivatives: Synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC
Shin, Hyunshun,Gennadios, Heather A.,Whittington, Douglas A.,Christianson, David W.
, p. 2617 - 2623 (2008/02/10)
The first committed step in lipid A biosynthesis is catalyzed by uridine diphosphate-(3-O-(R-3-hydroxymyristoyl))-N-acetylglucosamine deacetylase (LpxC), a zinc-dependent deacetylase, and inhibitors of LpxC may be useful in the development of antibacteria