79298-16-1

Usage

InChI:InChI=1/C12H16N2O5/c1-12(2)18-8-6-3-5-4-7(15)13-11(16)14(5)10(17-6)9(8)19-12/h5-6,8-10H,3-4H2,1-2H3,(H,13,15,16)/t5-,6-,8-,9-,10-/m1/s1

Upstream product

• 15083-09-7 5'-deoxy-2',3'-O-isopropylidene-5'-O-methanesulfonyl-uridine 
• 138840-72-9 5'-Anisyltelluro-5'-deoxy-2',3'-O-isopropylidene-uridine 
• 362-43-6 2',3'-O-isopropylideneuridine 
• 138840-73-0 5',6-Cyclo-5'-deoxy-5,6-dihydro-5-(2-thiopyridyl)-2',3'-O-isopropylidene-uridine 
• 27999-65-1 (3aS,4S,6R,6aR)-6-(2,4-Dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carbaldehyde 
• 59686-59-8 (6S,5'S)-6,5'-cyclo-5,6-dihydro-2',3'-O-isopropylideneuridine 
• 116457-89-7 C₁₆H₁₈N₄O₆S 

Relevant academic research and scientific papers

Synthesis of 5′,8-cyclopurine and of 5′,6-cyclodihydropyrimidine nucleosides using intramolecular radical cyclisation based on the aryl telluride radical exchange process

The synthesis of C-cyclopurine and C-cyclodihydropyrimidine nucleosides has been effected using 5′-aryltelluronucleosides. Generation of methyl radicals from the photolysis of the acetyl derivative of N-hydroxy-2-thiopyridone permitted, by radical exchang

A NOVEL STEREOSPECIFIC RADICAL CYCLIZATION OF 2',3'-O-ISOPROPYLIDENEURIDE AND -ADENOSINE 5'-ALDEHYDE TO THE CORRESPONDING 6,5'-CYCLODIHYDROURIDINE AND 8,5'-CYCLOADENOSINE DERIVATES

Treatment of 2',3'-O-isopropylideneuridine 5'-aldehyde with tributyltin hydride in the presence of azobisisobutyronitrile affords (6S,5'S)-cyclo-5,6-dihydro-2',3'-O-isopropylideneuridine in a stereospecific manner.A similar reaction with N6-benzoyl-2',3'-O-isopropylideneadenosine 5'-aldehyde leads to the corresponding 8,5'-cycloadenosine.